diffuse pigmentation of back and arms: macular amyloidosis or other?
نویسندگان
چکیده
the study was undertaken to answer the question that how many patients with pigmentation of back and arms actually have amyloid deposits in pathology. 44 patients presenting with diffuse pigmentation of back and arms (dpoba) were selected. skin biopsies were performed in all cases from the affected sites. on all formalin fixed and paraffin embedded specimens, the following histochemical stains were performed: haematoxylin and eosin (h&e;), congo red and immunohistochemical staining using anti-cytokeratin monoclonal antibody. in 9 of 44 cases (20%), amyloid deposits were found. in the remaining 35 cases (80%), h&e;, congo red and immunohistochemical staining failed to show any amyloid deposition. we were unable to find amyloid deposition in most of the patients presented with dpoba. it seems that the signs may be attributable other disorders with similar clinical but different pathophysiologic aspects.
منابع مشابه
Diffuse pigmentation of back and arms: macular amyloidosis or other?
The study was undertaken to answer the question that how many patients with pigmentation of back and arms actually have amyloid deposits in pathology. 44 patients presenting with diffuse pigmentation of back and arms (DPOBA) were selected. Skin biopsies were performed in all cases from the affected sites. On all formalin fixed and paraffin embedded specimens, the following histochemical stains ...
متن کاملPhotodistributed macular amyloidosis presenting as diffuse facial pigmentation mimicking melasma: the surprising reveal
National Skin Centre, 1 Mandalay Road, Singapore 308205 Primary cutaneous amyloidosis is a chronic pruritic disorder with characteristic amyloid deposits in the papillary dermis. The manifestations of primary localised cutaneous amyloidosis (PLCA) are usually confined to the skin. The aetiopathogenesis of PLCA has not been clearly elucidated. We report a patient who developed PLCA after a short...
متن کاملIdiopathic eruptive macular pigmentation.
We present the case of a 10-year-old girl with a six months history of disseminated asymptomatic, brown pigmented macules on the trunk and proximal parts of the extremities. The clinical picture, histological findings, and the course of disease were similar to those of idiopathic eruptive macular pigmentation. The cutaneous lesions gradually disappeared over the next two years without any treat...
متن کاملPrimary diffuse tracheobronchial amyloidosis.
The case is reported of a woman who died at the age of 36 years from obstructive respiratory failure due to diffuse tracheobronchial amyloidosis which had caused symptoms for six years. When first seen her symptoms of wheezing cough and mucopurulent sputum sometimes streaked with blood were of recent onset, but on bronchogram and bronchoscopy her disease was already widespread. Appearances at b...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
acta medica iranicaجلد ۵۱، شماره ۵، صفحات ۳۲۹-۳۳۳
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023